Slow motion video shows where 49ers running back Christian McCaffrey seemingly injured himself and ended his season.

Christian McCaffrey's injury against the Bills could be due to the heavy workload he received since returning to the 49ers.

The San Francisco 49ers are moving forward without star running back Christian McCaffrey or backup Jordan Mason for the ...

49ers head coach Kyle Shanahan told reporters Monday that McCaffrey suffered a posterior cruciate ligament (PCL) injury ...

A spate of injuries has derailed the 49ers' Super Bowl hopes his season, but the bigger question is if their title window has ...

Just when it seemed that San Francisco 49ers running back Christian McCaffrey was starting to find his rhythm, in a moment of ...

There are bad bye weeks, and then there are season-ruining bye weeks. This could be the latter for many teams needing a ...

The 49ers have lost three games in a row, but their season isn't dead yet. Sure, they're in last place in the NFC West, but ...

The 2024 season has been a renaissance for running backs. After years of toiling away on middling teams, Philadelphia Eagles ...

The San Francisco 49ers’ 35-10 Week 13 loss to the Buffalo Bills was costly in more ways than one. Not only did it make San ...

The San Francisco 49ers' brutal battle against the injury bug continues to get worse, as they have lost their two main running backs — Christian ...

The 49ers signed two running backs to their practice squad after Christian McCaffrey and Jordan Mason were placed on injured ...