On a snowy night in Orchard Park, N.Y., the Buffalo Bills clinched the AFC East title with a dominant win over the San Francisco 49ers.

What an enjoyable day to be the Buffalo Bills on Sunday, a date which the team took on the San Francisco 49ers in NFL Week 13 action. The Bills (10-2) ended up winning in a rout in a 35-10 final over the 49ers (5-7).

Fresh off of a blowout win against the San Francisco 49ers, the Buffalo Bills are riding high heading into their Week 14 clash with Matthew Stafford and the Los

Why would anyone consider backing them with Week 14 NFL bets? That's because they are coming off a mini-bye, playing at home, and welcoming a Saints team that isn't used to playing or practicing in the elements that New York City can present.

Potential Super Bowl opponents clash when the 49ers meet the Bills on Sunday Night Football. Our expert predictions expect a huge Bills win.

The Buffalo Bills continued their 2024 schedule with a Week 13 win over the San Francisco 49ers, 35-10. The Bills (1

The Buffalo Bills hammered the San Francisco 49ers 35-10 in a snow-filled rout led by Josh Allen’s 4 TDs. Colin Cowherd explains why he feels like this is the year for the Bills to win the Super Bowl.

The Buffalo Bills destroyed a desperate San Francisco 49ers team 35-10 at home on Sunday Night Football. The win is arguably Buffalo's most impressive during its seven-game winning streak. It improves the Bills to 10-2 on the year and secures a playoff spot for a fifth straight year.

An 8-year-old 49ers fan, who is a cancer survivor, was shoved by a Bills fan at Sunday’s game, causing her to fall from her seat. Her family said she was not hurt during the altercation, but was emotionally shaken.

An 8-year-old 49ers fan, who is a cancer survivor, was shoved by a Bills fan at Sunday’s game, causing her to fall from her seat. Mia DeCamilla’s family said she was not physically hurt during the altercation,